Ventromedial prefrontal cortex encodes a latent estimate of cumulative reward.
Humans and other animals accumulate resources, or wealth, by making successive risky decisions. If and how risk attitudes vary with wealth remains an open question. Here humans accumulated reward by accepting or rejecting successive monetary gambles within arbitrarily defined temporal contexts. Risk preferences changed substantially toward risk aversion as reward accumulated within a context, and blood oxygen level dependent (BOLD) signals in the ventromedial prefrontal cortex (PFC) tracked t...Expand abstract
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