Cross-calibration of dual-energy X-ray densitometers for a large, multi-center genetic study of osteoporosis.

Journal article

Osteoporosis is a common disease with a strong genetic component characterized by reduced bone mass and an increased risk of fragility fractures. Bone mineral density (BMD) is the most important determinant of osteoporotic fracture risk, but the genes responsible for BMD regulation and fracture are incompletely defined. To enable multi-center studies to examine the genetic influences on BMD there is a requirement to standardize measurements across different manufacturers of bone densitometers...

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Authors: Reid, D; Mackay, I; Wilkinson, S; Miller, C; Schuette, D

• Publication status: Published
• Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
• Volume: 17
• Issue: 1
• Pages: 125-132
• Publication date: 2006-01-01
• DOI: 10.1007/s00198-005-1936-y
• EISSN: 1433-2965
• ISSN: 0937-941X
• Language: English
• Keywords: Osteoporosis; Lumbar Vertebrae; Child; Adolescent; Humans; Bone Density; Genetic Predisposition to Disease; Male; Absorptiometry, Photon; Phantoms, Imaging; Calibration; Femur Neck; Reproducibility of Results; Adult; Female