Population-specific patterns of linkage disequilibrium in the human 5q31 region
- Linkage disequilibrium across the human genome is generally lower in West Africans than Europeans. However in the 5q31 region, which is rich in immune genes, we find significantly more examples of apparent nonrecombination between distant marker pairs in West Africans. Much of this effect is due to SNPs that are absent in Europeans, possibly reflecting recent positive selection in the West African population.
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher copy:
- Copyright holder:
- Nature Publishing Group
- Copyright date:
- The full-text of this article is not currently available in ORA, but you may be able to access the definitive version of the article via the publisher copy link on this record page.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record