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Quantification of circulating cell-free plasma DNA and endothelial gene RNA in patients with burns and relation to acute thermal injury.

Abstract:

BACKGROUND: Major burn represents a multi-system insult to the human body. Despite improvements in mortality and morbidity, reliable predictors of outcome are lacking. Raised levels of cell-free nucleic acids have been detected in various pathological processes including burns. We quantified circulating nucleic acids as potential objective measures of burn severity with predictive and prognostic value. METHODS: Expression of endothelial specific cell-free mRNA and cell-free DNA were measured...

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Publication status:
Published

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Publisher copy:
10.1016/j.burns.2007.10.003

Authors


Wainscoat, J More by this author
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Journal:
Burns : journal of the International Society for Burn Injuries
Volume:
34
Issue:
6
Pages:
809-816
Publication date:
2008-09-05
DOI:
EISSN:
1879-1409
ISSN:
0305-4179
URN:
uuid:bc8ae06f-c61a-4f23-81b5-ca19bbb48c06
Source identifiers:
125222
Local pid:
pubs:125222

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