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Engineered core-shell magnetic nanoparticle for MR dual-modal tracking and safe magnetic manipulation of ependymal cells in live rodents.

Abstract:

Tagging recognition group(s) on superparamagnetic iron oxide is known to aid localization (imaging), stimulation and separation of biological entities using magnetic resonance imaging (MRI) and magnetic agitation/separation (MAS) techniques. Despite the wide applicability of iron oxide nanoparticles in T2-weighted MRI and MAS, the quality of the images and safe manipulation of the exceptionally delicate neural cells in a live brain are currently the key challenges. Here, we demonstrate the en...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1088/1361-6528/aa96eb

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Inorganic Chemistry
Role:
Author
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Engineering and Physical Sciences Research Council More from this funder
University of Oxford More from this funder
Hong Kong Polytechnic University More from this funder
National Natural Science Foundation of China More from this funder
Hong Kong Baptist University More from this funder
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Publisher:
Institute of Physics Publisher's website
Journal:
Nanotechnology Journal website
Volume:
29
Issue:
1
Pages:
015102
Publication date:
2017-12-04
Acceptance date:
2017-10-30
DOI:
EISSN:
1361-6528
ISSN:
0957-4484
Pubs id:
pubs:811242
URN:
uri:bc6fffe4-2f2d-4d96-99cb-4d4a8decf42f
UUID:
uuid:bc6fffe4-2f2d-4d96-99cb-4d4a8decf42f
Local pid:
pubs:811242

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