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Journal article

Murine cardiosphere-derived cells are impaired by age but not by cardiac dystrophic dysfunction.

Abstract:

To be clinically relevant as a therapy for heart failure, endogenous progenitor cells must be isolated and expanded from aged and/or diseased tissue. Here, we investigated the effect of age and cardiac impairment resulting from lack of dystrophin on murine cardiosphere-derived cells (CDCs). CDCs were isolated and expanded from atrial biopsies from wild-type mice aged 1.5, 6, 18, and 24 months and from mdx mice aged 6 and 18 months. Cardiac function was measured in mdx mice and age-matched wil...

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Publication status:
Published

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Publisher copy:
10.1089/scd.2013.0388

Authors


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Publisher:
Mary Ann Liebert Inc.
Journal:
Stem cells and development
Volume:
23
Issue:
9
Pages:
1027-1036
Publication date:
2014-05-05
DOI:
EISSN:
1557-8534
ISSN:
1547-3287
URN:
uuid:bc6cc2aa-7d45-48bf-8b7e-57dd80cd8891
Source identifiers:
444273
Local pid:
pubs:444273

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