- Abstract:
-
To be clinically relevant as a therapy for heart failure, endogenous progenitor cells must be isolated and expanded from aged and/or diseased tissue. Here, we investigated the effect of age and cardiac impairment resulting from lack of dystrophin on murine cardiosphere-derived cells (CDCs). CDCs were isolated and expanded from atrial biopsies from wild-type mice aged 1.5, 6, 18, and 24 months and from mdx mice aged 6 and 18 months. Cardiac function was measured in mdx mice and age-matched wil...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1089/scd.2013.0388
-
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- Publisher:
- Mary Ann Liebert Inc.
- Journal:
- Stem cells and development
- Volume:
- 23
- Issue:
- 9
- Pages:
- 1027-1036
- Publication date:
- 2014-05-05
- DOI:
- EISSN:
-
1557-8534
- ISSN:
-
1547-3287
- URN:
-
uuid:bc6cc2aa-7d45-48bf-8b7e-57dd80cd8891
- Source identifiers:
-
444273
- Local pid:
- pubs:444273
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Murine cardiosphere-derived cells are impaired by age but not by cardiac dystrophic dysfunction.
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