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Journal article

Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4.

Abstract:

Antiviral immune responses of mice lacking interleukin-2 (IL-2) or IL-4 or both IL-2 and IL-4 (IL-2/4) were compared by using different viruses. Primary cytotoxic T-lymphocyte (CTL) responses against lymphocytic choriomeningitis virus (LCMV) were only moderately reduced in mice lacking IL-2 and were normal in mice lacking IL-4. Mice deficient in both interleukins exhibited variable and more strongly reduced but nevertheless in vivo protective LCMV-specific CTL responses. Similar results were ...

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Publication status:
Published

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Authors


Bachmann, MF More by this author
Schorle, H More by this author
Müller, W More by this author
Hengartner, H More by this author
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Journal:
Journal of virology
Volume:
69
Issue:
8
Pages:
4842-4846
Publication date:
1995-08-05
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:bc69dc34-8d8f-406d-8e4c-1ca80caa0c6c
Source identifiers:
469183
Local pid:
pubs:469183

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