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THE SYNTHESIS FROM D-XYLOSE OF THE POTENT AND SPECIFIC ENANTIOMERIC GLUCOSIDASE INHIBITORS, 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL AND 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL

Abstract:
Both enantiomers of 1,4-dideoxy-1,4-iminoarabinitol are specific inhibitors of glucosidases. The synthesis of 1,4-dideoxy-1,4-imino-D-arabinitol involves connecting C2 and C5 of xylose together with nitrogen, whereas the synthesis of 1,4-dideoxy-1.4-imino-L-arabinitol requires C1 and C4 of xylose to be joined together by nitrogen. 1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid found in Arachniodes standishii and Angylocalyx boutiqueanus. © 1986.
Publication status:
Published

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Journal:
TETRAHEDRON
Volume:
42
Issue:
20
Pages:
5685-5692
Publication date:
1986
DOI:
ISSN:
0040-4020
URN:
uuid:bc64fd3a-ee53-41c2-bbfd-95f285093467
Source identifiers:
42663
Local pid:
pubs:42663
Language:
English

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