Journal article icon

Journal article

The effect of acetazolamide on hypercapnic and eucapnic/poikilocapnic hypoxic ventilatory responses in normal subjects.

Abstract:

We have studied the effect of acetazolamide 500 mg bd for three days on ventilatory response to CO2 (HCVR) and hypoxia under both isocapnic and poikilocapnic conditions (isocapnic and poikilocapnic HVR) in five normal subjects. Although acetazolamide reduced calculated arterial pH (7.41 [SEM] 0.01 to 7.37 [SEM] 0.01: p less than 0.01) there was no significant change in either isocapnic HVR (with PetCO2 held at the post-drug resting level) or poikilocapnic HVR in terms of slope and ventilation...

Expand abstract

Actions


Access Document


Authors


Stradling, JR More by this author
Journal:
Pulmonary pharmacology
Volume:
3
Issue:
3
Pages:
151-154
Publication date:
1990
DOI:
ISSN:
0952-0600
URN:
uuid:bc5fbdf3-3536-46a4-bbaa-39214e9a4edd
Source identifiers:
71333
Local pid:
pubs:71333

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP