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Journal article

Butyrylcholinesterase K variant on chromosome 3 q is associated with Type II diabetes in white Caucasian subjects.

Abstract:

AIMS/HYPOTHESIS: To determine the association of three genes associated with Alzheimer's disease--butyrylcholinesterase (BcHE) on chromosome 3 q, alpha2 macroglobulin (alpha2M) on chromosome 12 p and apolipoprotein E (ApoE) on chromosome 19 q--with Type II (non-insulin-dependent) diabetes mellitus. METHODS: Frequencies of BcHE K variant, alpha2M insertion and/or deletion polymorphism, the ApoE common polymorphisms and promoter variants at ApoE-491 and -291, were examined by fluorescent RFLP i...

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Publication status:
Published

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Publisher copy:
10.1007/s001250100033

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
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Journal:
Diabetologia
Volume:
44
Issue:
12
Pages:
2227-2230
Publication date:
2001-12-05
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
URN:
uuid:bc507ae7-0d89-4216-9c4e-70c49ae2bd9d
Source identifiers:
20346
Local pid:
pubs:20346

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