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Chiral bicyclic tetramates as non-planar templates for chemical library synthesis.

Abstract:
Chemoselective Dieckmann cyclization reactions may be used on oxazolidine and thiazolidine templates derived from various aldehydes to access bicyclic tetramates, which have potential as templates for chemical library construction. Bioassay against Staphylococcus aureus and Escherichia coli showed that these systems have little or no intrinsic antibacterial bioactivity.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/cbdd.12110

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Publisher:
Wiley
Journal:
Chemical Biology and Drug Design More from this journal
Volume:
81
Issue:
5
Pages:
645-649
Publication date:
2013-04-24
DOI:
EISSN:
1747-0285
ISSN:
1747-0277
Language:
English
Keywords:
Pubs id:
pubs:375690
UUID:
uuid:bc495c60-37a5-4e1a-a5f8-25c860921a4b
Local pid:
pubs:375690
Source identifiers:
375690
Deposit date:
2013-11-16

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