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Chiral bicyclic tetramates as non-planar templates for chemical library synthesis.

Abstract:
Chemoselective Dieckmann cyclization reactions may be used on oxazolidine and thiazolidine templates derived from various aldehydes to access bicyclic tetramates, which have potential as templates for chemical library construction. Bioassay against Staphylococcus aureus and Escherichia coli showed that these systems have little or no intrinsic antibacterial bioactivity.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1111/cbdd.12110

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Publisher:
Wiley Publisher's website
Journal:
Chemical Biology and Drug Design Journal website
Volume:
81
Issue:
5
Pages:
645-649
Publication date:
2013-04-24
DOI:
EISSN:
1747-0285
ISSN:
1747-0277
URN:
uuid:bc495c60-37a5-4e1a-a5f8-25c860921a4b
Source identifiers:
375690
Local pid:
pubs:375690

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