Chiral bicyclic tetramates as non-planar templates for chemical library synthesis.
- Chemoselective Dieckmann cyclization reactions may be used on oxazolidine and thiazolidine templates derived from various aldehydes to access bicyclic tetramates, which have potential as templates for chemical library construction. Bioassay against Staphylococcus aureus and Escherichia coli showed that these systems have little or no intrinsic antibacterial bioactivity.
- Publication status:
- Peer review status:
- Peer reviewed
- Accepted manuscript
- Copyright holder:
- John Wiley and Sons
- Copyright date:
- © 2013 John Wiley and Sons A/S. Published on behalf of the American Peptide Society (APS). This is the accepted manuscript version of the article. The final version is available online from Wiley at: [10.1111/cbdd.12110].
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