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Journal article

Emerging gene therapies for cystic fibrosis

Abstract:

Introduction: Cystic fibrosis (CF) remains a life-threatening genetic disease, with few clinically effective treatment options. Gene therapy and gene editing strategies offer the potential for a one-time CF cure, irrespective of the CFTR mutation class.

Areas covered: We review emerging gene therapies and gene delivery strategies for the treatment of CF particularly viral and non-viral approaches with potential to treat CF.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/17476348.2019.1634547

Authors


More by this author
Institution:
University of Oxford
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Oxford college:
University College
Role:
Author
ORCID:
0000-0002-5264-054X
Publisher:
Taylor and Francis
Journal:
Expert Review of Respiratory Medicine More from this journal
Volume:
13
Issue:
8
Pages:
709-725
Publication date:
2019-06-19
Acceptance date:
2019-06-18
DOI:
EISSN:
1747-6356
ISSN:
1747-6348
Language:
English
Keywords:
Pubs id:
pubs:1023527
UUID:
uuid:bc48a2b8-bbbe-4797-9988-3e7660b65036
Local pid:
pubs:1023527
Source identifiers:
1023527
Deposit date:
2019-06-28

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