A new statistical approach to detecting significant activation in functional MRI.
There are many ways to detect activation patterns in a time series of observations at a single voxel in a functional magnetic resonance imaging study. The critical problem is to estimate the statistical significance, which depends on the estimation of both the magnitude of the response to the stimulus and the serial dependence of the time series and especially on the assumptions made in that estimation. We show that for experimental designs with periodic stimuli, only a few aspects of the ser...Expand abstract
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