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Brain death induces inflammation in the donor intestine.

Abstract:

BACKGROUND: Brain death donors are frequently used for transplantation. Previous studies showed that brain death (BD) negatively affects the immunological and inflammatory status of both liver and kidney. Because the intestine is increasingly used as a donor organ and no information on effects of BD on small intestine is available we performed this study. METHODS: We studied the inflammatory and apoptotic changes in donor intestine after BD induction. Brain death was induced in rats by infla...

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Publication status:
Published

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Publisher copy:
10.1097/tp.0b013e31817ba53a

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Transplantation
Volume:
86
Issue:
1
Pages:
148-154
Publication date:
2008-07-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:bbc25930-aeea-442a-acbb-87ac3b47c22e
Source identifiers:
190755
Local pid:
pubs:190755

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