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Early detection of cardiac involvement in systemic sclerosis assessed by tissue-Doppler echocardiography: relationship with neurohormonal activation and endothelial dysfunction.

Abstract:

OBJECTIVE: Cardiopulmonary complications are common in patients with systemic sclerosis (SSc). We assessed cardiac involvement in patients with SSc using echocardiography and investigated the association of N-terminal pro-brain natriuretic peptide (NT-proBNP) and asymmetric dimethylarginine (ADMA) with echocardiographic measures of myocardial function in sera of patients with SSc who had no symptoms of heart failure. METHODS: We prospectively studied 52 patients with SSc (mean age 55.7 +/- 1...

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Publication status:
Published

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Publisher copy:
10.3899/jrheum.090931

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Journal:
Journal of rheumatology
Volume:
37
Issue:
5
Pages:
993-999
Publication date:
2010-05-01
DOI:
EISSN:
1499-2752
ISSN:
0315-162X
Source identifiers:
105304

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