Journal article icon

Journal article

Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam.

Abstract:

Oxygenated derivatives of the monoterpene (+)-alpha-pinene are found in plant essential oils and used as fragrances and flavorings. (+)-alpha-Pinene is structurally related to (+)-camphor, the natural substrate of the heme monooxygenase cytochrome P450(cam) from Pseudomonas putida. The aim of the present work was to apply the current understanding of P450 substrate binding and catalysis to engineer P450(cam) for the selective oxidation of (+)-alpha-pinene. Consideration of the structures of (...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/ja028460a

Authors


Expand authors...
Journal:
Journal of the American Chemical Society
Volume:
125
Issue:
3
Pages:
705-714
Publication date:
2003-01-01
DOI:
EISSN:
1520-5126
ISSN:
0002-7863
Source identifiers:
32296
Language:
English
Keywords:
Pubs id:
pubs:32296
UUID:
uuid:bb739b10-ce7b-441a-9dca-4bbd863e715a
Local pid:
pubs:32296
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP