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Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids.

Abstract:

OBJECTIVE: SNPs identified from genome-wide association studies associate with lipid risk markers of cardiovascular disease. This study investigated whether these SNPs altered the plasma lipid response to diet in the 'RISCK' study cohort. METHODS: Participants (n=490) from a dietary intervention to lower saturated fat by replacement with carbohydrate or monounsaturated fat, were genotyped for 39 lipid-associated SNPs. The association of each individual SNP, and of the SNPs combined (using gen...

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Publication status:
Published

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Authors


Walker, CG More by this author
Griffin, BA More by this author
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Journal:
Atherosclerosis
Volume:
215
Issue:
2
Pages:
421-427
Publication date:
2011-04-05
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
URN:
uuid:bb67e1c1-35e5-4e63-8165-561b91f45ca3
Source identifiers:
417955
Local pid:
pubs:417955

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