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Inframolecular acid–base and coordination properties towards Na+ and Mg2+ of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species†

Abstract:

The myo-inositol phosphates (InsPs) are specific signalling metabolites ubiquitous in eukaryotic cells. Although Ins(1,3,4,5,6)P5 is the second most abundant member of the InsPs family, its certain biological roles are far from being elucidated, in part due to the large number of species formed by Ins(1,3,4,5,6)P5 in the presence of metal ions. In light of this, we have strived in the past to make a complete and at the same time "biological-user-friendly" description of the Ins(1,3,4,5,6)P 5 ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1039/c2dt31807e

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Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Dalton Transactions Journal website
Volume:
42
Issue:
17
Pages:
6021-6032
Publication date:
2012-11-09
Acceptance date:
2012-10-08
DOI:
ISSN:
1477-9234
Pubs id:
pubs:640293
URN:
uri:bb474a43-59fd-4bf0-ad2d-ed0420b515e6
UUID:
bb474a43-59fd-4bf0-ad2d-ed0420b515e6
Local pid:
pubs:640293
Paper number:
17
Keywords:

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