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Journal article

Collagenase penetrates human pancreatic islets following standard intraductal administration.

Abstract:

BACKGROUND: : To optimize human islet isolation, it is important to improve our understanding of the collagenase digestion phase. Previous studies of collagenase action were mostly concerned with optimizing its composition, but the delivery and distribution of collagenase at the islet-exocrine interface is likely to be important for liberation of intact islets. The aim of this study was to characterize collagenase distribution in relation to islets in infused human pancreases. METHODS: : Hum...

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Publication status:
Published

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Publisher copy:
10.1097/tp.0b013e318186df87

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Hughes, SJ More by this author
Partridge, CJ More by this author
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Journal:
Transplantation
Volume:
86
Issue:
7
Pages:
907-911
Publication date:
2008-10-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:bb371f2a-6e60-49af-a972-609bb746c8e5
Source identifiers:
102243
Local pid:
pubs:102243

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