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Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance

Abstract:
Background Spreading Plasmodium falciparum artemisinin drug resistance threatens global malaria public health gains. Limited data exist to define the extent of P. falciparum artemisinin resistance southeast of the Greater Mekong region in Malaysia.

Methods A clinical efficacy study of oral artesunate (total target dose 12 mg/kg) daily for 3 days was conducted in patients with uncomplicated falciparum malaria and a parasite count < 100,000/µL adm... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1186/s12936-018-2593-x

Authors


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ORCID:
0000-0001-9914-8352
William, T More by this author
Rajahram, GS More by this author
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More from this funder
Funding agency for:
Price, RN
Australian Centre of Research Excellence in Malaria Elimination More from this funder
Tropical Disease Research Regional Collaboration Initiative More from this funder
Publisher:
BMC Publisher's website
Journal:
Malaria Journal Journal website
Volume:
463
Issue:
17
Pages:
1-8
Publication date:
2018-12-10
Acceptance date:
2018-11-23
DOI:
EISSN:
1475-2875
Pubs id:
pubs:952334
URN:
uri:bb2045c3-7cc3-4e90-b3a5-60745ca559d1
UUID:
uuid:bb2045c3-7cc3-4e90-b3a5-60745ca559d1
Local pid:
pubs:952334

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