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Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients.

Abstract:

BACKGROUND: Campath 1H is a depleting, humanized anti-CD52 monoclonal antibody that has now been used in 31 renal allograft recipients. The results have been very encouraging and are presented herein. METHODS: Campath 1H was administered, intravenously, in a dose of 20 mg, on day 0 and day 1 after renal transplant. Low-dose cyclosporine (Neoral) was then initiated at 72 hr after transplant. These patients were maintained on low-dose monotherapy with cyclosporine. RESULTS: At present, the mea...

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Moffatt, SD More by this author
Friend, PJ More by this author
Jamieson, NV More by this author
Bradley, JA More by this author
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Journal:
Transplantation
Volume:
68
Issue:
10
Pages:
1613-1616
Publication date:
1999-11-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:bb1f10a8-7f29-4d4c-9fa2-1b5ff99e140e
Source identifiers:
26673
Local pid:
pubs:26673

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