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Rapid and efficient mapping of regional ventilation in the rat lung using hyperpolarized 3He with Flip Angle Variation for Offset of RF and Relaxation (FAVOR).

Abstract:

A novel imaging method is presented, Flip Angle Variation for Offset of RF and Relaxation (FAVOR), for rapid and efficient measurement of rat lung ventilation using hyperpolarized helium-3 (3He) gas. The FAVOR technique utilizes variable flip angles to remove the cumulative effect of RF pulses and T1 relaxation on the hyperpolarized gas signal and thereby eliminates the need for intervening air wash-out breaths and multiple cycles of 3He wash-in breaths before each image. The former allows an...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.21582

Authors


Santyr, GE More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Ouriadov, A More by this author
Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume:
59
Issue:
6
Pages:
1304-1310
Publication date:
2008-06-05
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:bafddf04-f37b-4118-b11e-7af0c3abe936
Source identifiers:
441915
Local pid:
pubs:441915

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