Journal article
Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
- Abstract:
-
Two polysaccharide-based hydrogels made of only κ-carrageenan (4%; w/v) or of a mixture of methylcellulose:κ-carrageenan (2%; w/v) were used to encapsulate cationic nioplexes. These vesicular particles were made of a synthetic aminolipid and polysorbate-80 (Tween-80), as a non-ionic surfactant agent. According to oscillatory rheological measurements, the presence of nioplexes did not compromise the mechanical integrity of the gels. In vitro niosomal release experiments demonstrated the libera...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Royal Society of Chemistry
- Journal:
- Journal of Materials Chemistry B More from this journal
- Volume:
- 5
- Issue:
- 37
- Pages:
- 7756-7767
- Publication date:
- 2017-08-31
- Acceptance date:
- 2017-08-28
- DOI:
- EISSN:
-
2050-7518
- ISSN:
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2050-750X
Item Description
- Pubs id:
-
pubs:745462
- UUID:
-
uuid:bae79ba6-f4bf-4bac-8df7-b30823bdc3e0
- Local pid:
-
pubs:745462
- Source identifiers:
-
745462
- Deposit date:
-
2018-06-07
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- Copyright holder:
- Grijalvo et al
- Copyright date:
- 2017
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