Journal article icon

Journal article

Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study.

Abstract:

AIMS: Endogenous cardiac progenitor cells, expanded from explants via cardiosphere formation, present a promising cell source to prevent heart failure following myocardial infarction. Here we used cine-magnetic resonance imaging (MRI) to track administered cardiosphere-derived cells (CDCs) and to measure changes in cardiac function over four months in the infarcted rat heart. METHODS AND RESULTS: CDCs, cultured from neonatal rat heart, comprised a heterogeneous population including cells expr...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0025669

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
More by this author
Institution:
University of Oxford
More by this author
Institution:
University of Oxford
More by this author
Institution:
University of Oxford
Expand authors...
British Heart Foundation More from this funder
Malaysian Ministry of Higher Education More from this funder
Marie Curie International More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
6
Issue:
10
Pages:
Article: e25669
Publication date:
2011
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:bac5e5f0-f8c5-4569-9ef8-53ada3f93818
Source identifiers:
198760
Local pid:
pubs:198760

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP