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Journal article

Case-control studies of association in structured or admixed populations.

Abstract:

Case-control tests for association are an important tool for mapping complex-trait genes. But population structure can invalidate this approach, leading to apparent associations at markers that are unlinked to disease loci. Family-based tests of association can avoid this problem, but such studies are often more expensive and in some cases--particularly for late-onset diseases--are impractical. In this review article we describe a series of approaches published over the past 2 years which use...

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Publication status:
Published

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Publisher copy:
10.1006/tpbi.2001.1543

Authors


Journal:
Theoretical population biology
Volume:
60
Issue:
3
Pages:
227-237
Publication date:
2001-11-05
DOI:
EISSN:
1096-0325
ISSN:
0040-5809
URN:
uuid:ba9f1557-aada-42bc-9739-e77c8313f595
Source identifiers:
49972
Local pid:
pubs:49972

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