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Conditioned respiratory threat in the subdivisions of the human periaqueductal gray

Abstract:

The sensation of breathlessness is the most threatening symptom of respiratory disease. The different subdivisions of the midbrain periaqueductal gray (PAG) are intricately (and differentially) involved in integrating behavioural responses to threat in animals, while the PAG has previously only been considered as a single entity in human research. Here we investigate how these individual PAG columns are differently involved with respiratory threat. Eighteen healthy subjects were conditione...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.7554/eLife.12047

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More by this author
Institution:
University of Oxford
Department:
Oxford, MSD
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD
More from this funder
Funding agency for:
Pattinson, K
National Institute for Health Research More from this funder
Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife
Volume:
5
Pages:
e12047
Publication date:
2016-02-27
DOI:
ISSN:
2050-084X
URN:
uuid:ba8ab06f-8366-49f2-b754-5d306a697ec3
Source identifiers:
607822
Local pid:
pubs:607822

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