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Assessing transmission blockade in Plasmodium spp.

Abstract:
Here we describe a series of methods that can be used to assess the activities of "vaccines," drugs, and genetically modified vectors, for their abilities to inhibit transmission of Plasmodium from its vertebrate to its mosquito hosts. The selection of method to be used is determined by the purpose of the experiment, which can include the determination of the site/time of activity, and/or the potential reduction in transmission achieved.

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Authors


Blagborough, AM More by this author
Delves, MJ More by this author
Ramakrishnan, C More by this author
Butcher, G More by this author
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Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
923
Pages:
577-600
Publication date:
2013
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:ba84546d-fd7e-412c-97ff-a72e428a5c14
Source identifiers:
369943
Local pid:
pubs:369943

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