Journal article
EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method
- Abstract:
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Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively). Conversely, treatment with C2C12 myotube-conditioned medium enhanced myogenic differentiation. Ultrafiltration-size exclusion liquid chromatography (UF-SEC) was used to isolate EVs and non-EV extracellular protein in parallel from C2C12 myobla...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 6.6MB, Terms of use)
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- Publisher copy:
- 10.1016/j.omtn.2023.07.005
Authors
Bibliographic Details
- Publisher:
- Cell Press
- Journal:
- Molecular Therapy - Nucleic Acids More from this journal
- Volume:
- 33
- Pages:
- 511-528
- Publication date:
- 2023-07-14
- Acceptance date:
- 2023-07-11
- DOI:
- EISSN:
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2162-2531
- Pmid:
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37602275
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
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1510253
- Local pid:
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pubs:1510253
- Deposit date:
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2023-09-21
Terms of use
- Copyright holder:
- Hanson et al.
- Copyright date:
- 2023
- Rights statement:
- Copyright © 2023 The Author(s). This is an open access article published under CC BY 4.0.
- Licence:
- CC Attribution (CC BY)
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