- Abstract:
-
High-throughput sequencing of the B cell receptor (BCR) repertoire can provide rapid characterization of the B cell response in a wide variety of applications in health, after vaccination and in infectious, inflammatory and immune-driven disease, and is starting to yield clinical applications. However, the interpretation of repertoire data is compromised by a lack of studies to assess the intra and inter-individual variation in the BCR repertoire over time in healthy individuals. We applied a...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.6mb)
-
- Publisher copy:
- 10.3389/fimmu.2015.00531
-
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- Funding agency for:
- Kelly, DF
- Publisher:
- Frontiers Publisher's website
- Journal:
- Frontiers in immunology Journal website
- Volume:
- 6
- Issue:
- OCT
- Pages:
- 531
- Publication date:
- 2015
- DOI:
- EISSN:
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1664-3224
- ISSN:
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1664-3224
- URN:
-
uuid:ba614a2e-2751-410e-af47-78b9b668a771
- Source identifiers:
-
575195
- Local pid:
- pubs:575195
- Copyright holder:
- Galson et al.
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Galson, Trück, Fowler, Münz, Cerundolo, Pollard, Lunter and Kelly. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Journal article
In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire
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+ National Institute for Health Research Oxford Biomedical Research Centre
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National Institute for Health Research
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Medical Research Council
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