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Journal article

In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire

Abstract:

High-throughput sequencing of the B cell receptor (BCR) repertoire can provide rapid characterization of the B cell response in a wide variety of applications in health, after vaccination and in infectious, inflammatory and immune-driven disease, and is starting to yield clinical applications. However, the interpretation of repertoire data is compromised by a lack of studies to assess the intra and inter-individual variation in the BCR repertoire over time in healthy individuals. We applied a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fimmu.2015.00531

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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics
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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics
Cerundolo, V More by this author
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Funding agency for:
Pollard, AJ
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Funding agency for:
Pollard, AJ
National Institute for Health Research More from this funder
Medical Research Council More from this funder
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Publisher:
Frontiers Publisher's website
Journal:
Frontiers in immunology Journal website
Volume:
6
Issue:
OCT
Pages:
531
Publication date:
2015
DOI:
EISSN:
1664-3224
ISSN:
1664-3224
URN:
uuid:ba614a2e-2751-410e-af47-78b9b668a771
Source identifiers:
575195
Local pid:
pubs:575195

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