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P644Mechanisms of myocardial nitroso redox imbalance following elective cardiac surgery on cardiopulmonary bypass.

Abstract:

BACKGROUND AND AIMS: The mechanisms responsible for myocardial stunning after cardiac surgery are only partially understood, although ischemia - reperfusion (IR) injury associated with cardio pulmonary bypass (CPB) may play an important role. Reactive oxygen species and nitric oxide have been implicated in both myocardial injury and cardio protection suggesting that identification of their sources may refine therapeutic strategies. Here we investigated the effect of cardioplegia, CPB and repe...

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Publication status:
Published

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Publisher copy:
10.1093/cvr/cvu098.70

Authors


Jayaram, R More by this author
Goodfellow, N More by this author
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Journal:
Cardiovascular research
Volume:
103 Suppl 1
Issue:
suppl 1
Pages:
S117
Publication date:
2014-07-05
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
URN:
uuid:ba058d04-8b2c-4ae9-96db-29c3cf24f7c6
Source identifiers:
475913
Local pid:
pubs:475913
Language:
English

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