Journal article
The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent
- Abstract:
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With the exception of ApoE4, genome-wide association studies have failed to identify strong genetic risk factors for late-onset Alzheimer's disease, despite strong evidence of heritability, suggesting that many low penetrance genes may be involved. Additionally, the nature of the identified genetic risk factors and their relation to disease pathology is also largely obscure. Previous studies have found that a cancer-associated variant of the cell cycle inhibitor gene p21cip1 is associated wit...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.1MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0114050
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Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS One More from this journal
- Volume:
- 10
- Issue:
- 1
- Pages:
- Article e0114050
- Publication date:
- 2015-01-27
- Acceptance date:
- 2014-10-09
- DOI:
- ISSN:
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1932-6203
- Pmid:
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25625488
Item Description
- Language:
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English
- Keywords:
-
- Pubs id:
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pubs:505673
- UUID:
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uuid:b9dca866-49ba-4465-808a-e6837451b9ba
- Local pid:
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pubs:505673
- Source identifiers:
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505673
- Deposit date:
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2016-12-18
Terms of use
- Copyright holder:
- Yates et al
- Copyright date:
- 2015
- Notes:
- © 2015 Yates et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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