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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

Abstract:

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome sequence of the Brown Norway (BN) rat strain. The sequence represents a high-quality 'draft' covering over 90% of the genome. The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. Thi...

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Publication status:
Published

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Publisher copy:
10.1038/nature02426

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Journal:
Nature
Volume:
428
Issue:
6982
Pages:
493-521
Publication date:
2004-04-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:b9cd145f-834f-440b-8472-db07fa16ab8a
Source identifiers:
54276
Local pid:
pubs:54276

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