Journal article icon

Journal article

HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand.

Abstract:

INTRODUCTION: Cytotoxic T cells specific for the hematopoietic system-restricted minor histocompatibility antigens HA-1 and HA-2 are potential tools for the treatment of relapsed leukemia after minor histocompatibility antigen mismatched bone marrow transplantation. HA-1/HA-2-specific cytotoxic T cells with strong cytotoxic activity against HA-1/HA-2 positive target cells can be generated in vitro using HA-1 and HA-2 peptide-pulsed dendritic cells as antigen presenting cells. MATERIAL AND MET...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/sj.thj.6200065

Authors


Expand authors...
Journal:
The hematology journal : the official journal of the European Haematology Association / EHA
Volume:
1
Issue:
6
Pages:
403-410
Publication date:
2000-01-01
DOI:
ISSN:
1466-4860
URN:
uuid:b9c70107-0d6e-4d85-8d13-c6280fb17547
Source identifiers:
95858
Local pid:
pubs:95858

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP