- Abstract:
-
INTRODUCTION: Cytotoxic T cells specific for the hematopoietic system-restricted minor histocompatibility antigens HA-1 and HA-2 are potential tools for the treatment of relapsed leukemia after minor histocompatibility antigen mismatched bone marrow transplantation. HA-1/HA-2-specific cytotoxic T cells with strong cytotoxic activity against HA-1/HA-2 positive target cells can be generated in vitro using HA-1 and HA-2 peptide-pulsed dendritic cells as antigen presenting cells. MATERIAL AND MET...
Expand abstract - Publisher copy:
- 10.1038/sj.thj.6200065
-
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- Journal:
- The hematology journal : the official journal of the European Haematology Association / EHA
- Volume:
- 1
- Issue:
- 6
- Pages:
- 403-410
- Publication date:
- 2000-01-01
- DOI:
- ISSN:
-
1466-4860
- URN:
-
uuid:b9c70107-0d6e-4d85-8d13-c6280fb17547
- Source identifiers:
-
95858
- Local pid:
- pubs:95858
- Language:
- English
- Keywords:
- Copyright date:
- 2000
Journal article
HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand.
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