Journal article
Melanosome-autonomous regulation of size and number: The OA1 receptor sustains PMEL expression
- Abstract:
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Summary: Little is known as to how cells ensure that organelle size and number are coordinated to correctly couple organelle biogenesis to the demands of proliferation or differentiation. OA1 is a melanosome-associated G-protein-coupled receptor involved in melanosome biogenesis during melanocyte differentiation. Cells lacking OA1 contain fewer, but larger, mature melanosomes. Here, we show that OA1 loss of function reduces both the basal expression and the α-melanocyte-stimulating hormone/cA...
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- Publisher copy:
- 10.1111/pcmr.12239
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Authors
Bibliographic Details
- Publisher:
- Blackwell Publishing Ltd
- Journal:
- Pigment Cell and Melanoma Research
- Volume:
- 27
- Issue:
- 4
- Pages:
- 565-579
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
1755-148X
- ISSN:
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1755-1471
- Source identifiers:
-
472040
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:472040
- UUID:
-
uuid:b9b5646a-8b49-48a1-817e-85d04a2accf0
- Local pid:
- pubs:472040
- Deposit date:
- 2014-07-05
Terms of use
- Copyright date:
- 2014
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