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Neural transposition in the Drosophila brain: is it all bad news?

Abstract:

Transposition of mobile genetic elements can radically alter genome structure and sequence. In doing so, they can alter gene expression and cellular function. Perhaps unsurprisingly, this potentially catastrophic process is heavily constrained, especially in the germ line where aberrations lead to sterility or could be passed onto the next generation. However, recent studies in mammals and fruit flies suggest that transposition happens at measurable levels in the brain, and possibly more so i...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Treiber, C More by this author
Journal:
Advances in genetics
Volume:
86
Pages:
65-92
Publication date:
2014-01-05
DOI:
ISSN:
0065-2660
URN:
uuid:b99d60bf-efd0-4611-a4ae-66ce894d8306
Source identifiers:
482546
Local pid:
pubs:482546

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