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Journal article

A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice.

Abstract:

BACKGROUND: Since its first appearance in the USA in 1999, West Nile virus (WNV) has spread in the Western hemisphere and continues to represent an important public health concern. In the absence of effective treatment, there is a medical need for the development of a safe and efficient vaccine. Live attenuated WNV vaccines have shown promise in preclinical and clinical studies but might carry inherent risks due to the possibility of reversion to more virulent forms. Subunit vaccines based o...

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Publication status:
Published

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Publisher copy:
10.1186/1743-422x-7-146

Authors


Jennings, GT More by this author
Martina, BE More by this author
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Journal:
Virology journal
Volume:
7
Issue:
1
Pages:
146
Publication date:
2010
DOI:
EISSN:
1743-422X
ISSN:
1743-422X
URN:
uuid:b99610d0-a440-4e32-836a-13c03d88e72a
Source identifiers:
422341
Local pid:
pubs:422341

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