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The role of lic2B in lipopolysaccharide biosynthesis in Haemophilus influenzae strain Eagan.

Abstract:

Lipopolysaccharide (LPS) biosynthesis in Haemophilus influenzae involves genes from the lic2 locus that are required for chain extension from the middle heptose (HepII) of the conserved triheptosyl inner-core moiety. Lic2C initiates the process by attaching the first glucose to HepII, but the gene encoding for the enzyme adding the next β-D-Glcp- is uncharacterized. Lic2B is the candidate glucosyltransferase; however, in previous investigations, mutation of lic2B resulted in no hexose extensi...

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Journal:
Carbohydrate research
Volume:
346
Issue:
10
Pages:
1262-1266
Publication date:
2011-07-05
DOI:
EISSN:
1873-426X
ISSN:
0008-6215
URN:
uuid:b986581e-b8c4-49f8-89b6-fe0da96eb6d7
Source identifiers:
162111
Local pid:
pubs:162111

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