- Abstract:
-
BACKGROUND: Returning stenosis in Crohn's disease (CD) patients is poorly understood. After resection, newly developed strictures are seen within 10 years in 50% to 70%. Matrix metalloproteinases (MMPs) are involved in matrix-turnover processes. This study analyzes spatial expression of MMP-1, MMP-3, MMP-9, tissue inhibitor of MMP-1, and collagen III to get better insight in tissue remodeling of terminal ileum of CD patients. METHODS: Expressions were analyzed on mRNA and the protein level (...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1097/01.mib.0000231568.43065.ed
-
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- Journal:
- Inflammatory bowel diseases
- Volume:
- 12
- Issue:
- 9
- Pages:
- 863-869
- Publication date:
- 2006-09-05
- DOI:
- EISSN:
-
1536-4844
- ISSN:
-
1078-0998
- URN:
-
uuid:b9476e05-6c5c-4ace-a039-3225bcc9bcf5
- Source identifiers:
-
190866
- Local pid:
- pubs:190866
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Matrix metalloproteinases as profibrotic factors in terminal ileum in Crohn's disease.
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