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Journal article

Matrix metalloproteinases as profibrotic factors in terminal ileum in Crohn's disease.

Abstract:

BACKGROUND: Returning stenosis in Crohn's disease (CD) patients is poorly understood. After resection, newly developed strictures are seen within 10 years in 50% to 70%. Matrix metalloproteinases (MMPs) are involved in matrix-turnover processes. This study analyzes spatial expression of MMP-1, MMP-3, MMP-9, tissue inhibitor of MMP-1, and collagen III to get better insight in tissue remodeling of terminal ileum of CD patients. METHODS: Expressions were analyzed on mRNA and the protein level (...

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Publication status:
Published

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Journal:
Inflammatory bowel diseases
Volume:
12
Issue:
9
Pages:
863-869
Publication date:
2006-09-05
DOI:
EISSN:
1536-4844
ISSN:
1078-0998
URN:
uuid:b9476e05-6c5c-4ace-a039-3225bcc9bcf5
Source identifiers:
190866
Local pid:
pubs:190866

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