Journal article
Genetic correction of PSA values using sequence variants associated with PSA levels.
- Abstract:
-
Measuring serum levels of the prostate-specific antigen (PSA) is the most common screening method for prostate cancer. However, PSA levels are affected by a number of factors apart from neoplasia. Notably, around 40% of the variability of PSA levels in the general population is accounted for by inherited factors, suggesting that it may be possible to improve both sensitivity and specificity by adjusting test results for genetic effects. To search for sequence variants that associate with PSA ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1126/scitranslmed.3001513
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Authors
Bibliographic Details
- Journal:
- Science translational medicine
- Volume:
- 2
- Issue:
- 62
- Pages:
- 62ra92
- Publication date:
- 2010-12-01
- DOI:
- EISSN:
-
1946-6242
- ISSN:
-
1946-6234
- Source identifiers:
-
120599
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:120599
- UUID:
-
uuid:b93a2708-6313-40f7-92c8-0f2889c2c84a
- Local pid:
- pubs:120599
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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