Genetic correction of PSA values using sequence variants associated with PSA levels.

Gudmundsson, J; Besenbacher, S; Sulem, P; Gudbjartsson, DF; Olafsson, I; Arinbjarnarson, S; Agnarsson, BA; Benediktsdottir, KR; Isaksson, HJ; Kostic, JP; Gudjonsson, SA; Stacey, SN; Gylfason, A; Sigurdsson, A; Holm, H; Bjornsdottir, US; Eyjolfsson, GI; Navarrete, S; Fuertes, F; Garcia-Prats, MD; Polo, E; Checherita, IA; Jinga, M; Badea, P; Aben, KK; Schalken, JA; van Oort, IM; Sweep, FC; Helfand, BT; Davis, M; Donovan, JL; Hamdy, FC; Kristjansson, K; Gulcher, JR; Masson, G; Kong, A; Catalona, WJ; Mayordomo, JI; Geirsson, G; Einarsson, GV; Barkardottir, RB; Jonsson, E; Jinga, V; Mates, D; Kiemeney, LA; Neal, DE; Thorsteinsdottir, U; Rafnar, T; Stefansson, K

Abstract:

Measuring serum levels of the prostate-specific antigen (PSA) is the most common screening method for prostate cancer. However, PSA levels are affected by a number of factors apart from neoplasia. Notably, around 40% of the variability of PSA levels in the general population is accounted for by inherited factors, suggesting that it may be possible to improve both sensitivity and specificity by adjusting test results for genetic effects. To search for sequence variants that associate with PSA ...

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APA Style

Gudmundsson, J., Besenbacher, S., Sulem, P., Gudbjartsson, D. F., Olafsson, I., Arinbjarnarson, S., Agnarsson, B. A., Benediktsdottir, K. R., Isaksson, H. J., Kostic, J. P., Gudjonsson, S. A., Stacey, S. N., Gylfason, A., Sigurdsson, A., Holm, H., Bjornsdottir, U. S., Eyjolfsson, G. I., Navarrete, S., Fuertes, F., … Stefansson, K. (2010). Genetic correction of PSA values using sequence variants associated with PSA levels. Science Translational Medicine, 2(62), 62ra92.

MLA Style

Gudmundsson, J., et al. “Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels.” Science Translational Medicine, vol. 2, no. 62, Science translational medicine, 2010, p. 62ra92.

Chicago Style

Gudmundsson, J, S Besenbacher, P Sulem, DF Gudbjartsson, I Olafsson, S Arinbjarnarson, BA Agnarsson, et al. 2010. “Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels.” Science Translational Medicine 2 (62): 62ra92.
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