Journal article
Thrombocytopenia impairs host defense against Burkholderia pseudomallei (Melioidosis)
- Abstract:
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Background Infection with the gram-negative bacillus Burkholderia pseudomallei (melioidosis) is an important cause of pneumosepsis in Southeast Asia and has a mortality of up to 40%. We aimed to assess the role of platelets in the host response against B. pseudomallei infection. Methods Association between platelet counts and mortality was determined in 1160 patients with culture-proven melioidosis. Mice treated with (low- or high-dose) platelet-depleting an... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 726.0KB, Terms of use)
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- Publisher copy:
- 10.1093/infdis/jiy541
Authors
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Journal of Infectious Diseases More from this journal
- Volume:
- 219
- Issue:
- 4
- Pages:
- 648–659
- Publication date:
- 2018-10-11
- Acceptance date:
- 2018-09-26
- DOI:
- EISSN:
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1537-6613
- ISSN:
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0022-1899
- Pmid:
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30312422
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:929656
- UUID:
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uuid:b8f0bc33-5c7f-4a58-ab94-146b5472393a
- Local pid:
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pubs:929656
- Source identifiers:
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929656
- Deposit date:
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2018-11-14
Terms of use
- Copyright holder:
- Birnie et al
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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