- Abstract:
-
Background Infection with the gram-negative bacillus Burkholderia pseudomallei (melioidosis) is an important cause of pneumosepsis in Southeast Asia and has a mortality of up to 40%. We aimed to assess the role of platelets in the host response against B. pseudomallei infection. Methods Association between platelet counts and mortality was determined in 1160 patients with culture-proven melioidosis. Mice treated with (low- or high-dose) platelet-depleting an... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 219
- Issue:
- 4
- Pages:
- 648–659
- Publication date:
- 2018-10-11
- Acceptance date:
- 2018-09-26
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- Pubs id:
-
pubs:929656
- URN:
-
uri:b8f0bc33-5c7f-4a58-ab94-146b5472393a
- UUID:
-
uuid:b8f0bc33-5c7f-4a58-ab94-146b5472393a
- Local pid:
- pubs:929656
- Language:
- English
- Keywords:
- Copyright holder:
- Birnie et al.
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Thrombocytopenia impairs host defense against Burkholderia pseudomallei (Melioidosis)
Actions
Authors
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record