Cortical lesions induce an increase in cell number and PSA-NCAM expression in the subventricular zone of adult rats.

Journal article

The subventricular zone (SVZ) bordering the lateral ventricle is one of the few regions of adult brain that contains dividing cells. These cells can differentiate into neurons in vivo after migration into the olfactory bulb and in vitro in the presence of appropriate growth factors. Little is known, however, about the fate of these cells in vivo after brain injury in adults. We examined cell number and expression of differentiation markers in the SVZ of adult rats after cortical lesions. Aspi...

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Authors: Szele, F; Chesselet, M

• Publication status: Published
• Journal: Journal of comparative neurology
• Volume: 368
• Issue: 3
• Pages: 439-454
• Publication date: 1996-05-01
• DOI: 10.1002/(sici)1096-9861(19960506)368:3<439::aid-cne9>3.0.co;2-6
• EISSN: 1096-9861
• ISSN: 0021-9967
• Language: English
• Keywords: Intermediate Filament Proteins; Neostriatum; Cell Count; Neurons; Rats; Cerebral Ventricles; Neural Cell Adhesion Molecules; Neuroglia; Male; Animals; Bromodeoxyuridine; Nerve Tissue Proteins; Growth Substances; Immunohistochemistry; Cell Movement; Sialic Acids; Rats, Sprague-Dawley; Biological Markers