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Thesis

The role of the CtIP gene as a genetic susceptibility factor for radiation leukaemogenesis

Abstract:

Exposure to ionising radiation increases the risk of cancer, including acute myeloid leukemia (AML), which is the most common myeloid leukaemia. The C-terminal binding protein (CtBP)-interacting protein (CtIP), which is essential for embryonic development and possibly functions as a tumour suppressor, has been identified as a strong candidate for susceptibility to radiation-induced AML (rAML).

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Institution:
University of Oxford
Oxford college:
St Catherine's College
Department:
Oxford Institute for Radiation Oncology

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:b8cc6940-e780-4ebd-8bf5-a655a52570d2
Local pid:
ora:10202
Language:
English
Keywords:
Subjects:

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