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Exploitation of stem cell plasticity.

Abstract:

For many years, adult haemopoietic stem cells (HSCs) have been considered 'plastic' in their proliferative and differentiation capacities. Recently, evidence that supports newer concepts of adult stem cell plasticity has been reported. In particular, stem cells from haemopoietic tissues seem to have 'extraordinary' abilities to generate or switch between haemopoietic and nonhaemopoietic lineages, exhibiting an unexpected degree of developmental or differentiation potential. The mechanisms by ...

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Authors


Martin-Rendon, E More by this author
Journal:
Transfusion medicine (Oxford, England)
Volume:
13
Issue:
6
Pages:
325-349
Publication date:
2003-12-05
DOI:
EISSN:
1365-3148
ISSN:
0958-7578
URN:
uuid:b8ba30cf-5e58-48ac-8f7a-de0b9f2448d5
Source identifiers:
324087
Local pid:
pubs:324087

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