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Thesis

Exploring the role of the RNA-binding protein SRSF3 in the developing heart

Alternative title:
SRSF3 is required for epicardium formation and EMT during murine heart development
Abstract:

Understanding the molecular processes that govern cardiovascular development has the potential to inform regenerative strategies for disease states. Due to their versatile roles, epicardial cells are an attractive therapeutic target. However, using epicardial cells for therapy is hindered by our limited understanding of epicardial biology.

The embryonic epicardium is one of the main regulators of cardiovascular development, functioning to secrete essential growth factors and produc...

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Division:
MSD
Department:
Doctoral Training Centre - MSD
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
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Name:
British Heart Foundation
Grant:
FS/12/69/30008
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:b8a03682-e0cb-4f15-bddb-cc77f823c673
Deposit date:
2020-02-05

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