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A sliding selectivity scale for lipid binding to membrane proteins

Abstract:

Biological membranes form barriers that are essential for cellular integrity and compartmentalisation. Proteins in the membrane have co-evolved with their hydrophobic lipid environment, which serves as a solvent for proteins with very diverse requirements. As a result, their interactions range from non-selective to highly discriminating. Mass spectrometry enables us to monitor how lipids interact with membrane proteins and assess their effects on structure and dynamics. Recent studies illustr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.sbi.2016.04.005

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
More from this funder
Funding agency for:
Robinson, C
Grant:
Research Professorship
More from this funder
Funding agency for:
Robinson, C
Grant:
Research Professorship
More from this funder
Funding agency for:
Gault, J
Grant:
Advanced Investigator Award (26851) (IMPRESS)
More from this funder
Funding agency for:
Robinson, C
Gault, J
Grant:
Research Professorship
Advanced Investigator Award (26851) (IMPRESS)
Publisher:
Elsevier
Journal:
Current opinion in structural biology More from this journal
Volume:
39
Pages:
54-60
Publication date:
2016-01-01
DOI:
EISSN:
1879-033X
ISSN:
0959-440X
Language:
English
Pubs id:
pubs:619910
UUID:
uuid:b89723b2-2374-4c40-9870-99ab6d13fef1
Local pid:
pubs:619910
Source identifiers:
619910
Deposit date:
2016-05-26

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