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Melatonin In Acute Mania Investigation (MIAMI‐UK): A randomised controlled trial of add‐on melatonin in bipolar disorder

Abstract:

Objectives:
Current options for treating emergent episodes of hypomania and mania in bipolar disorder are limited. Our objective was to compare the effectiveness and safety of add‐on melatonin in hypomania or mania over three weeks as a well‐tolerated therapy.


Methods:
A randomised, double‐blind, parallel‐group, three‐week comparison of modified release melatonin (n=21) vs placebo (n=20) in adult bipolar patients aged 18‐65 years....

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/bdi.12944

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Bipolar Disorders Journal website
Volume:
23
Issue:
2
Pages:
176-185
Place of publication:
Denmark
Publication date:
2020-07-03
Acceptance date:
2020-05-31
DOI:
EISSN:
1399-5618
ISSN:
1398-5647
Language:
English
Keywords:
Pubs id:
1109058
Local pid:
pubs:1109058
Deposit date:
2020-06-05

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