Journal article icon

Journal article

Selective photostimulation of genetically chARGed neurons.

Abstract:

To permit direct functional analyses of neural circuits, we have developed a method for stimulating groups of genetically designated neurons optically. Coexpression of the Drosophila photoreceptor genes encoding arrestin-2, rhodopsin (formed by liganding opsin with retinal), and the alpha subunit of the cognate heterotrimeric G protein--an explosive combination we term "chARGe"--sensitizes generalist vertebrate neurons to light. Illumination of a mixed population of neurons elicits action pot...

Expand abstract

Actions


Access Document


Authors


Journal:
Neuron
Volume:
33
Issue:
1
Pages:
15-22
Publication date:
2002-01-01
DOI:
EISSN:
1097-4199
ISSN:
0896-6273
Source identifiers:
322560

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP