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CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys.

Abstract:
Systemic administration of CCK-8S (1 or 10 micrograms/kg IP) markedly inhibited L-dopa-induced dyskinesias in parkinsonian monkeys, but did not interfere with locomotor stimulation by L-dopa. CCK analogues may be useful antidyskinetic agents for improved control of Parkinson's disease.
Publication status:
Published

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Publisher copy:
10.1212/wnl.40.4.717

Authors


Rupniak, NM More by this author
Steventon, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Neurology
Volume:
40
Issue:
4
Pages:
717-718
Publication date:
1990-04-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:b84e92fb-a03d-4671-bf1b-9e5ac7119347
Source identifiers:
29402
Local pid:
pubs:29402

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