Journal article
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs.
- Abstract:
-
Nicotinic acid adenine dinucleotide phosphate (NAADP) mobilizes Ca(2+) in many cells and species. Unlike other Ca(2+)-mobilizing messengers, NAADP mobilizes Ca(2+) from an unknown store that is not the endoplasmic reticulum, the store traditionally associated with messenger-mediated Ca(2+) signaling. Here, we demonstrate the presence of a Ca(2+) store in sea urchin eggs mobilized by NAADP that is dependent on a proton gradient maintained by an ATP-dependent vacuolar-type proton pump. Moreover...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0092-8674(02)01082-6
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Bibliographic Details
- Journal:
- Cell
- Volume:
- 111
- Issue:
- 5
- Pages:
- 703-708
- Publication date:
- 2002-11-01
- DOI:
- EISSN:
-
1097-4172
- ISSN:
-
0092-8674
- Source identifiers:
-
106523
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:106523
- UUID:
-
uuid:b84a22a0-302e-45ed-b39a-706981b2d3a1
- Local pid:
- pubs:106523
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2002
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