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Journal article

miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons.

Abstract:

An array of signals regulating the early stages of postnatal subventricular zone (SVZ) neurogenesis has been identified, but much less is known regarding the molecules controlling late stages. Here, we investigated the function of the activity-dependent and morphogenic microRNA miR-132 on the synaptic integration and survival of olfactory bulb (OB) neurons born in the neonatal SVZ. In situ hybridization revealed that miR-132 expression occurs at the onset of synaptic integration in the OB. Us...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0038174

Authors


Pathania, M More by this author
Torres-Reveron, J More by this author
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National Institutes of Health More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
7
Issue:
5
Pages:
Article: e38174
Publication date:
2012
DOI:
EISSN:
1932-6203
URN:
uuid:b839cadc-3c57-4484-ae3a-eeb4229dda6a
Source identifiers:
340062
Local pid:
pubs:340062

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